If you are using the Nova Launcher v 1.3.2 the app drawer will fail after installing Android 4.2. The solution is to download the Nova Launcher v 1.3.3beta1.
1.3.3beta1 Nov 13, 0112•Fix dock on Android 4.2
•Update Stock Jellybean theme for 4.2 icons (Camera, Clock)
•Fix unread counts in drawer not always updating
•Fix Widget Picker on some Samsung 4.1 devices
•Fix drawer tab sometimes not being selectable
•Optimizations
Open Nova Launcher Settings > Check for updates > Menu (3 dots in upper right corner) > Tap Beta and Download the Beta APK then install.