Any changes to the stock system can cause issues with an update. This includes apps that install binaries, frozen or disabled apps, build.prop edits, etc. If you are rooted, there is a chance that something may be changed. Like others have said, us experienced users will be testing to see what will be the smoothest way to proceed with the update. You seem to already be prepared. I would suggest having a Nandroid backup. Be patient and let us do the rest...
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